|
KMID : 0358819780050010051
|
|
Journal of Korean Society of Plastic and Reconstructive Surgeons
1978 Volume.5 No. 1 p.51 ~ p.55
|
|
|
Experimental Study of Tissue Reactions to Autografts and Allografts of Cartilage and Silastic Impants
|
|
李世一/Lee, Se Il
李英浩/柳在德/Lee, Young Ho/Lew, Jae Duk
|
|
|
Abstract
|
|
|
Both experimental and clinical evidence indicate that cartilage (autografts and allografts) can survive free transplantation. In autografts the chondroc7tes survive as living cells which continue to service and maintain their cartilaginous matrix. Fresh cartilage Homografts with living cell would be as satisfactory as autogenous graft were it not for the fact that host cells tend to remove the matrix of these homograf is and thus reduce the bulk of the cartilage transplant. But body response to allografts is not well known. Body reponse to silicone implants where sponges, semisolids, such as gels, or solids (rubber) is similar and has been well documented. The authors examined early tissue response to cartilage autografts and allografts and silastic implants and the results of light microscope are summerized as follows;
1. Aggregation of polymorphoneuclear cells is prominent in all series(postoperative 1st day).
2. In cartilage graft, there are many PMN cells and monocytes underneath the graft with capillary engorgement. Many fibroblasts are seen. The findings of silastic implants showed similar to the former except prominent capillary engorgement without active proliferation (postoperative 3rd day).
3. There are increased number of monocytes, fibroblasts and increased collagen fibers in all series. Capillary engorgement is prominent in Homograft and active phagocytosis is typical in silastic implants (postoperative 7th day).
4. In autograft there are a few PMN cells, many fibroblasts and rollagenization (postoperative 14th day) and complete healing of wound is present on postoperative 28th day. Complete collagenization are seen in homograft (POD#14 and 28). In cases of silastic implants, complete collagenization is typical findings on postoper ative 14th day. Findings on 28th day, there are chronic nonspecific inflammation with accumulation of foreign body giant cells.
|
|
|
KEYWORD
|
|
|
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
  
|
|